Human Gene AC025165.3 (ENST00000651284.1) Description and Page Index
  Description: AC025165.3 (from geneSymbol)
RefSeq Summary (NM_005726): This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010].
Gencode Transcript: ENST00000651284.1
Gencode Gene: ENSG00000257921.6
Transcript (Including UTRs)
   Position: hg38 chr12:57,772,660-57,797,554 Size: 24,895 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg38 chr12:57,772,725-57,787,050 Size: 14,326 Coding Exon Count: 5 

Page IndexSequence and LinksMicroarray ExpressionRNA StructureOther SpeciesmRNA Descriptions
Other NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:57,772,660-57,797,554)mRNA (may differ from genome)Protein (200 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
ExonPrimerGeneCardsMGIPubMedStanford SOURCEUniProtKB

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -30.6065-0.471 Picture PostScript Text
3' UTR -438.101578-0.278 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  AK308981 - Homo sapiens cDNA, FLJ99022.
AF455816 - Homo sapiens hepatocellular carcinoma-associated antigen HCA557a mRNA, complete cds.
BC016395 - Homo sapiens family with sequence similarity 119, member B, mRNA (cDNA clone MGC:16818 IMAGE:3882414), complete cds.
BC099841 - Homo sapiens family with sequence similarity 119, member B, mRNA (cDNA clone MGC:119654 IMAGE:40010149), complete cds.
BC103501 - Homo sapiens family with sequence similarity 119, member B, transcript variant 1, mRNA (cDNA clone MGC:119656 IMAGE:40010152), complete cds.
AK292276 - Homo sapiens cDNA FLJ77367 complete cds, highly similar to Homo sapiens hepatocellularcarcinoma-associated antigen HCA557a, transcript variant 1, mRNA.
AK024983 - Homo sapiens cDNA: FLJ21330 fis, clone COL02466.
AL050100 - Homo sapiens mRNA; cDNA DKFZp586D0919 (from clone DKFZp586D0919).
CU677623 - Synthetic construct Homo sapiens gateway clone IMAGE:100016821 5' read FAM119B mRNA.
AB528834 - Synthetic construct DNA, clone: pF1KE0458, Homo sapiens FAM119B gene for family with sequence similarity 119, member B, without stop codon, in Flexi system.
AM393242 - Synthetic construct Homo sapiens clone IMAGE:100002383 for hypothetical protein (FAM119B gene).
AM393762 - Synthetic construct Homo sapiens clone IMAGE:100002384 for hypothetical protein (FAM119B gene).
KJ898564 - Synthetic construct Homo sapiens clone ccsbBroadEn_07958 METTL21B gene, encodes complete protein.
JD196598 - Sequence 177622 from Patent EP1572962.
KM576716 - Homo sapiens clone METTL21B-TSFM_M2-T2-T5out mRNA sequence.
LF384691 - JP 2014500723-A/192194: Polycomb-Associated Non-Coding RNAs.
MA620268 - JP 2018138019-A/192194: Polycomb-Associated Non-Coding RNAs.
AK313453 - Homo sapiens cDNA, FLJ93997.
AK304621 - Homo sapiens cDNA FLJ50108 complete cds, highly similar to Elongation factor Ts, mitochondrial precursor.
BC022862 - Homo sapiens Ts translation elongation factor, mitochondrial, mRNA (cDNA clone MGC:23697 IMAGE:4076880), complete cds.
AK295323 - Homo sapiens cDNA FLJ60259 complete cds, highly similar to Elongation factor Ts, mitochondrial precursor.
BC093068 - Homo sapiens Ts translation elongation factor, mitochondrial, mRNA (cDNA clone MGC:111185 IMAGE:30722527), complete cds.
AF110399 - Homo sapiens elongation factor Ts mRNA, nuclear gene encoding mitochondrial protein, complete cds.
KJ898158 - Synthetic construct Homo sapiens clone ccsbBroadEn_07552 TSFM gene, encodes complete protein.
KR711974 - Synthetic construct Homo sapiens clone CCSBHm_00034394 TSFM (TSFM) mRNA, encodes complete protein.
L37936 - Human nuclear-encoded mitochondrial elongation factor Ts (EF-Ts) mRNA, 3' end of cds.
LF324076 - JP 2014500723-A/131579: Polycomb-Associated Non-Coding RNAs.
MA559653 - JP 2018138019-A/131579: Polycomb-Associated Non-Coding RNAs.
LF324075 - JP 2014500723-A/131578: Polycomb-Associated Non-Coding RNAs.
MA559652 - JP 2018138019-A/131578: Polycomb-Associated Non-Coding RNAs.
LF324071 - JP 2014500723-A/131574: Polycomb-Associated Non-Coding RNAs.
MA559648 - JP 2018138019-A/131574: Polycomb-Associated Non-Coding RNAs.
LF324070 - JP 2014500723-A/131573: Polycomb-Associated Non-Coding RNAs.
MA559647 - JP 2018138019-A/131573: Polycomb-Associated Non-Coding RNAs.
LF324069 - JP 2014500723-A/131572: Polycomb-Associated Non-Coding RNAs.
MA559646 - JP 2018138019-A/131572: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A494C1I5, AK304621, uc287hdd.1
UCSC ID: uc287hdd.1
RefSeq Accession: NM_005726

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.