Human Gene SEMA6C (ENST00000368913.7) from GENCODE V44
Description: Homo sapiens semaphorin 6C (SEMA6C), transcript variant 1, mRNA. (from RefSeq NM_001178061) RefSeq Summary (NM_001178061): This gene encodes a member of the semaphorin family. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration. [provided by RefSeq, May 2010]. Gencode Transcript: ENST00000368913.7 Gencode Gene: ENSG00000143434.17 Transcript (Including UTRs) Position: hg38 chr1:151,131,685-151,146,457 Size: 14,773 Total Exon Count: 20 Strand: - Coding Region Position: hg38 chr1:151,132,484-151,142,621 Size: 10,138 Coding Exon Count: 18
ID:SEM6C_HUMAN DESCRIPTION: RecName: Full=Semaphorin-6C; AltName: Full=Semaphorin-Y; Short=Sema Y; Flags: Precursor; FUNCTION: Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: In adult tissues, expressed only in skeletal muscle. SIMILARITY: Belongs to the semaphorin family. SIMILARITY: Contains 1 PSI domain. SIMILARITY: Contains 1 Sema domain. SEQUENCE CAUTION: Sequence=BAB47498.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H3T2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
