Human Gene KCNK2 (ENST00000391894.6) from GENCODE V44
Description: Homo sapiens potassium two pore domain channel subfamily K member 2 (KCNK2), transcript variant 2, mRNA. (from RefSeq NM_014217) RefSeq Summary (NM_014217): This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000391894.6 Gencode Gene: ENSG00000082482.14 Transcript (Including UTRs) Position: hg38 chr1:215,083,124-215,235,217 Size: 152,094 Total Exon Count: 7 Strand: + Coding Region Position: hg38 chr1:215,083,307-215,235,145 Size: 151,839 Coding Exon Count: 7
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.