Human Gene ANXA11 (ENST00000438331.5) from GENCODE V44
Description: Homo sapiens annexin A11 (ANXA11), transcript variant c, mRNA. (from RefSeq NM_145869) RefSeq Summary (NM_145869): This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, Dec 2015]. Gencode Transcript: ENST00000438331.5 Gencode Gene: ENSG00000122359.18 Transcript (Including UTRs) Position: hg38 chr10:80,150,889-80,205,572 Size: 54,684 Total Exon Count: 17 Strand: - Coding Region Position: hg38 chr10:80,155,853-80,172,861 Size: 17,009 Coding Exon Count: 14
ID:Q5T0G8_HUMAN DESCRIPTION: RecName: Full=Annexin; DOMAIN: A pair of annexin repeats may form one binding site for calcium and phospholipid (By similarity). SIMILARITY: Belongs to the annexin family. SIMILARITY: Contains 4 annexin repeats.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q5T0G8
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.