Human Gene THY1 (ENST00000284240.10) from GENCODE V44
Description: Homo sapiens Thy-1 cell surface antigen (THY1), transcript variant 1, mRNA. (from RefSeq NM_006288) RefSeq Summary (NM_006288): This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Gencode Transcript: ENST00000284240.10 Gencode Gene: ENSG00000154096.14 Transcript (Including UTRs) Position: hg38 chr11:119,415,476-119,423,172 Size: 7,697 Total Exon Count: 4 Strand: - Coding Region Position: hg38 chr11:119,419,408-119,420,905 Size: 1,498 Coding Exon Count: 3
ID:THY1_HUMAN DESCRIPTION: RecName: Full=Thy-1 membrane glycoprotein; AltName: Full=CDw90; AltName: Full=Thy-1 antigen; AltName: CD_antigen=CD90; Flags: Precursor; FUNCTION: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor (By similarity). SIMILARITY: Contains 1 Ig-like V-type (immunoglobulin-like) domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P04216
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.