Human Gene PANX3 (ENST00000284288.3) from GENCODE V44
Description: Homo sapiens pannexin 3 (PANX3), mRNA. (from RefSeq NM_052959) RefSeq Summary (NM_052959): The protein encoded by this gene belongs to the innexin family. Innexin family members are known to be the structural components of gap junctions. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000284288.3 Gencode Gene: ENSG00000154143.3 Transcript (Including UTRs) Position: hg38 chr11:124,611,428-124,620,356 Size: 8,929 Total Exon Count: 4 Strand: + Coding Region Position: hg38 chr11:124,611,557-124,619,935 Size: 8,379 Coding Exon Count: 4
ID:PANX3_HUMAN DESCRIPTION: RecName: Full=Pannexin-3; FUNCTION: Structural component of the gap junctions and the hemichannels. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Potential). Cell junction, gap junction. SIMILARITY: Belongs to the pannexin family. WEB RESOURCE: Name=Wikipedia; Note=Pannexin entry; URL="http://en.wikipedia.org/wiki/Pannexin";
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96QZ0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.