Human Gene FOXM1 (ENST00000359843.8) from GENCODE V44
Description: Homo sapiens forkhead box M1 (FOXM1), transcript variant 2, mRNA. (from RefSeq NM_021953) RefSeq Summary (NM_021953): The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]. Gencode Transcript: ENST00000359843.8 Gencode Gene: ENSG00000111206.13 Transcript (Including UTRs) Position: hg38 chr12:2,857,680-2,877,174 Size: 19,495 Total Exon Count: 9 Strand: - Coding Region Position: hg38 chr12:2,858,638-2,874,478 Size: 15,841 Coding Exon Count: 8
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q53Y49
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.