Human Gene ACYP1 (ENST00000238618.8) from GENCODE V44
Description: Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 1, mRNA. (from RefSeq NM_001107) RefSeq Summary (NM_001107): This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]. Gencode Transcript: ENST00000238618.8 Gencode Gene: ENSG00000119640.9 Transcript (Including UTRs) Position: hg38 chr14:75,053,243-75,064,024 Size: 10,782 Total Exon Count: 3 Strand: - Coding Region Position: hg38 chr14:75,053,444-75,063,553 Size: 10,110 Coding Exon Count: 2
ID:ACYP1_HUMAN DESCRIPTION: RecName: Full=Acylphosphatase-1; EC=3.6.1.7; AltName: Full=Acylphosphatase, erythrocyte isozyme; AltName: Full=Acylphosphatase, organ-common type isozyme; AltName: Full=Acylphosphate phosphohydrolase 1; FUNCTION: Its physiological role is not yet clear. CATALYTIC ACTIVITY: An acylphosphate + H(2)O = a carboxylate + phosphate. TISSUE SPECIFICITY: Organ-common type isozyme is found in many different tissues. SIMILARITY: Belongs to the acylphosphatase family. SIMILARITY: Contains 1 acylphosphatase-like domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P07311
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
