Human Gene CKB (ENST00000348956.7) from GENCODE V44
Description: Homo sapiens creatine kinase B (CKB), transcript variant 1, mRNA. (from RefSeq NM_001823) RefSeq Summary (NM_001823): The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000348956.7 Gencode Gene: ENSG00000166165.14 Transcript (Including UTRs) Position: hg38 chr14:103,519,667-103,522,830 Size: 3,164 Total Exon Count: 8 Strand: - Coding Region Position: hg38 chr14:103,519,864-103,522,493 Size: 2,630 Coding Exon Count: 7
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.