Human Gene KLF13 (ENST00000307145.4) from GENCODE V44
  Description: Homo sapiens Kruppel like factor 13 (KLF13), transcript variant 1, mRNA. (from RefSeq NM_015995)
RefSeq Summary (NM_015995): KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008].
Gencode Transcript: ENST00000307145.4
Gencode Gene: ENSG00000169926.11
Transcript (Including UTRs)
   Position: hg38 chr15:31,326,835-31,377,899 Size: 51,065 Total Exon Count: 2 Strand: +
Coding Region
   Position: hg38 chr15:31,327,213-31,372,299 Size: 45,087 Coding Exon Count: 2 

Page IndexSequence and LinksPrimersMalaCardsCTDRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesGeneReviews
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr15:31,326,835-31,377,899)mRNA (may differ from genome)Protein (288 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGencode
OMIMPubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

-  MalaCards Disease Associations
  MalaCards Gene Search: KLF13
Diseases sorted by gene-association score: chromosome 15q13.3 microdeletion syndrome (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 34.87 RPKM in Brain - Cerebellum
Total median expression: 767.57 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -199.40378-0.528 Picture PostScript Text
3' UTR -2196.105600-0.392 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein Sequence     

-  Descriptions from all associated GenBank mRNAs
  AF132599 - Homo sapiens RANTES factor of late activated T lymphocytes-1 mRNA, complete cds.
BC035503 - Homo sapiens Kruppel-like factor 13, mRNA (cDNA clone IMAGE:4563309).
BC010438 - Homo sapiens Kruppel-like factor 13, mRNA (cDNA clone MGC:4201 IMAGE:2823301), complete cds.
BC013946 - Homo sapiens Kruppel-like factor 13, mRNA (cDNA clone MGC:2531 IMAGE:2823301), complete cds.
DQ595388 - Homo sapiens piRNA piR-61500, complete sequence.
BC012741 - Homo sapiens Kruppel-like factor 13, mRNA (cDNA clone MGC:15271 IMAGE:3940815), complete cds.
JC513953 - Sequence 4206 from Patent WO2014113089.
LQ071541 - Sequence 1865 from Patent EP2964234.
AF150628 - Homo sapiens transcription factor NSLP1 mRNA, complete cds.
JD129017 - Sequence 110041 from Patent EP1572962.
KJ534876 - Homo sapiens clone KLF13_iso-A_adult-A15 Kruppel-like factor 13 isoform A (KLF13) mRNA, partial cds, alternatively spliced.
KJ535015 - Homo sapiens clone KLF13_iso-B_adult-A13 Kruppel-like factor 13 isoform B (KLF13) mRNA, complete cds, alternatively spliced.
DQ587638 - Homo sapiens piRNA piR-54750, complete sequence.
JD117657 - Sequence 98681 from Patent EP1572962.
AL390127 - Homo sapiens mRNA; cDNA DKFZp761P06121 (from clone DKFZp761P06121).
DQ598126 - Homo sapiens piRNA piR-36192, complete sequence.
DQ574999 - Homo sapiens piRNA piR-43111, complete sequence.
BC012782 - Homo sapiens Kruppel-like factor 13, mRNA (cDNA clone IMAGE:3943625), partial cds.
BC064552 - Homo sapiens cDNA clone IMAGE:5553940, partial cds.
DQ575850 - Homo sapiens piRNA piR-43962, complete sequence.
DQ595098 - Homo sapiens piRNA piR-61210, complete sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000307145.1, ENST00000307145.2, ENST00000307145.3, NM_015995, uc001zfo.1, uc001zfo.2, uc001zfo.3, uc001zfo.4, uc001zfo.5, X5DNR2
UCSC ID: ENST00000307145.4
RefSeq Accession: NM_015995
CCDS: CCDS10025.1

-  GeneReviews for This Gene
  GeneReviews article(s) related to gene KLF13:
mdel15q13_3 (15q13.3 Recurrent Deletion)

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.