Human Gene CRLF3 (ENST00000324238.7) from GENCODE V44
Description: Homo sapiens cytokine receptor like factor 3 (CRLF3), transcript variant 1, mRNA. (from RefSeq NM_015986) RefSeq Summary (NM_015986): This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012]. Gencode Transcript: ENST00000324238.7 Gencode Gene: ENSG00000176390.12 Transcript (Including UTRs) Position: hg38 chr17:30,782,684-30,824,692 Size: 42,009 Total Exon Count: 8 Strand: - Coding Region Position: hg38 chr17:30,784,187-30,824,651 Size: 40,465 Coding Exon Count: 8
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8IUI8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
