Human Gene ZFP82 (ENST00000392161.4) from GENCODE V44
  Description: Homo sapiens ZFP82 zinc finger protein (ZFP82), transcript variant 1, mRNA. (from RefSeq NM_133466)
Gencode Transcript: ENST00000392161.4
Gencode Gene: ENSG00000181007.9
Transcript (Including UTRs)
   Position: hg38 chr19:36,388,630-36,418,644 Size: 30,015 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg38 chr19:36,392,741-36,409,789 Size: 17,049 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:36,388,630-36,418,644)mRNA (may differ from genome)Protein (532 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
UniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Zinc finger protein 82 homolog; Short=Zfp-82; AltName: Full=Zinc finger protein 545;
FUNCTION: May be involved in transcriptional regulation.
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 13 C2H2-type zinc fingers.
SIMILARITY: Contains 1 KRAB domain.
SEQUENCE CAUTION: Sequence=BAB85534.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAB85534.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;

-  Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.00 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 64.86 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -96.40231-0.417 Picture PostScript Text
3' UTR -1111.404111-0.270 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001909 - Krueppel-associated_box
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF01352 - KRAB box

ModBase Predicted Comparative 3D Structure on Q8N141
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter

Cellular Component:
GO:0005622 intracellular
GO:0005634 nucleus

-  Descriptions from all associated GenBank mRNAs
  JD231553 - Sequence 212577 from Patent EP1572962.
AB075828 - Homo sapiens mRNA for KIAA1948 protein.
JD219930 - Sequence 200954 from Patent EP1572962.
JD517853 - Sequence 498877 from Patent EP1572962.
JD366637 - Sequence 347661 from Patent EP1572962.
JD106026 - Sequence 87050 from Patent EP1572962.
JD517852 - Sequence 498876 from Patent EP1572962.
JD075052 - Sequence 56076 from Patent EP1572962.
JD072665 - Sequence 53689 from Patent EP1572962.
JD444679 - Sequence 425703 from Patent EP1572962.
JD291657 - Sequence 272681 from Patent EP1572962.
JD120905 - Sequence 101929 from Patent EP1572962.
JD344067 - Sequence 325091 from Patent EP1572962.
JD482750 - Sequence 463774 from Patent EP1572962.
JD425449 - Sequence 406473 from Patent EP1572962.
JD474475 - Sequence 455499 from Patent EP1572962.
JD431185 - Sequence 412209 from Patent EP1572962.
JD471864 - Sequence 452888 from Patent EP1572962.
JD378207 - Sequence 359231 from Patent EP1572962.
JD276153 - Sequence 257177 from Patent EP1572962.
GU388429 - Homo sapiens zinc finger protein 85 (ZFP82) mRNA, complete cds.
AL834267 - Homo sapiens mRNA; cDNA DKFZp761C148 (from clone DKFZp761C148).
AK074942 - Homo sapiens cDNA FLJ90461 fis, clone NT2RP3001976, moderately similar to ZINC FINGER PROTEIN 84.
JD438545 - Sequence 419569 from Patent EP1572962.
JD429933 - Sequence 410957 from Patent EP1572962.
JD080437 - Sequence 61461 from Patent EP1572962.
JD295546 - Sequence 276570 from Patent EP1572962.
JD048055 - Sequence 29079 from Patent EP1572962.
JD350769 - Sequence 331793 from Patent EP1572962.
JD326406 - Sequence 307430 from Patent EP1572962.
JD247282 - Sequence 228306 from Patent EP1572962.
JD238626 - Sequence 219650 from Patent EP1572962.
AK315709 - Homo sapiens cDNA, FLJ96808.
HQ258012 - Synthetic construct Homo sapiens clone IMAGE:100072321 Unknown protein gene, encodes complete protein.
KJ900569 - Synthetic construct Homo sapiens clone ccsbBroadEn_09963 ZFP82 gene, encodes complete protein.
EU446629 - Synthetic construct Homo sapiens clone IMAGE:100070229; IMAGE:100011838; FLH257316.01L zinc finger protein 545 (ZNF545) gene, encodes complete protein.
EU832297 - Synthetic construct Homo sapiens clone HAIB:100067326; DKFZo008B1227 zinc finger protein 545 protein (ZNF545) gene, encodes complete protein.
EU832381 - Synthetic construct Homo sapiens clone HAIB:100067410; DKFZo004B1228 zinc finger protein 545 protein (ZNF545) gene, encodes complete protein.
AB384651 - Synthetic construct DNA, clone: pF1KA1948, Homo sapiens ZNF545 gene for zinc finger protein 545, complete cds, without stop codon, in Flexi system.
JD314886 - Sequence 295910 from Patent EP1572962.
JD314887 - Sequence 295911 from Patent EP1572962.
JD290178 - Sequence 271202 from Patent EP1572962.
JD406781 - Sequence 387805 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000392161.1, ENST00000392161.2, ENST00000392161.3, KIAA1948, NM_133466, Q8N141, Q8NC63, Q8TF53, uc002ody.1, uc002ody.2, uc002ody.3, ZFP82_HUMAN, ZNF545
UCSC ID: ENST00000392161.4
RefSeq Accession: NM_133466
Protein: Q8N141 (aka ZFP82_HUMAN)
CCDS: CCDS12493.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.