Human Gene EEF1B2 (ENST00000236957.9) from GENCODE V44
Description: Homo sapiens eukaryotic translation elongation factor 1 beta 2 (EEF1B2), transcript variant 2, mRNA. (from RefSeq NM_021121) RefSeq Summary (NM_021121): This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000236957.9 Gencode Gene: ENSG00000114942.14 Transcript (Including UTRs) Position: hg38 chr2:206,159,585-206,162,928 Size: 3,344 Total Exon Count: 7 Strand: + Coding Region Position: hg38 chr2:206,159,980-206,162,883 Size: 2,904 Coding Exon Count: 6
ID:EF1B_HUMAN DESCRIPTION: RecName: Full=Elongation factor 1-beta; Short=EF-1-beta; FUNCTION: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. SUBUNIT: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma. INTERACTION: P26641:EEF1G; NbExp=3; IntAct=EBI-354334, EBI-351467; PTM: Phosphorylation affects the GDP/GTP exchange rate. SIMILARITY: Belongs to the EF-1-beta/EF-1-delta family. SIMILARITY: Contains 1 GST C-terminal domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P24534
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.