Human Gene DEFB119 (ENST00000376321.4) from GENCODE V44
Description: Homo sapiens defensin beta 119 (DEFB119), transcript variant 7, non-coding RNA. (from RefSeq NR_126440) RefSeq Summary (NM_153289): This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]. Gencode Transcript: ENST00000376321.4 Gencode Gene: ENSG00000180483.7 Transcript (Including UTRs) Position: hg38 chr20:31,377,164-31,390,590 Size: 13,427 Total Exon Count: 2 Strand: - Coding Region Position: hg38 chr20:31,377,246-31,390,483 Size: 13,238 Coding Exon Count: 2
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N690
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.