Human Gene OSBPL2 (ENST00000313733.9) from GENCODE V44
Description: Homo sapiens oxysterol binding protein like 2 (OSBPL2), transcript variant 2, mRNA. (from RefSeq NM_144498) RefSeq Summary (NM_144498): This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]. Gencode Transcript: ENST00000313733.9 Gencode Gene: ENSG00000130703.17 Transcript (Including UTRs) Position: hg38 chr20:62,238,521-62,296,183 Size: 57,663 Total Exon Count: 14 Strand: + Coding Region Position: hg38 chr20:62,256,185-62,293,887 Size: 37,703 Coding Exon Count: 13
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H1P3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
