Human Gene PAQR9 (ENST00000340634.6) from GENCODE V44
  Description: Homo sapiens progestin and adipoQ receptor family member 9 (PAQR9), transcript variant 1, mRNA. (from RefSeq NM_198504)
Gencode Transcript: ENST00000340634.6
Gencode Gene: ENSG00000188582.10
Transcript (Including UTRs)
   Position: hg38 chr3:142,954,585-142,963,674 Size: 9,090 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg38 chr3:142,962,203-142,963,336 Size: 1,134 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:142,954,585-142,963,674)mRNA (may differ from genome)Protein (377 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCHPRDLynxMalacardsMGIneXtProt
OMIMPubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: PAQR9_HUMAN
DESCRIPTION: RecName: Full=Progestin and adipoQ receptor family member 9; AltName: Full=Progestin and adipoQ receptor family member IX;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
TISSUE SPECIFICITY: Expression levels vary widely in a range of tissues.
SIMILARITY: Belongs to the ADIPOR family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 11.15 RPKM in Testis
Total median expression: 21.52 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -179.30338-0.530 Picture PostScript Text
3' UTR -2028.247618-0.266 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR004254 - HlyIII-related

Pfam Domains:
PF03006 - Haemolysin-III related

ModBase Predicted Comparative 3D Structure on Q6ZVX9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein SequenceProtein Sequence   
AlignmentAlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0008289 lipid binding

Biological Process:
GO:0043401 steroid hormone mediated signaling pathway
GO:0048545 response to steroid hormone

Cellular Component:
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AK093381 - Homo sapiens cDNA FLJ36062 fis, clone TESTI2018697.
LF208582 - JP 2014500723-A/16085: Polycomb-Associated Non-Coding RNAs.
MA444159 - JP 2018138019-A/16085: Polycomb-Associated Non-Coding RNAs.
BC030124 - Homo sapiens cDNA clone IMAGE:4816505.
AK123932 - Homo sapiens cDNA FLJ41938 fis, clone PERIC2006035.
LF212302 - JP 2014500723-A/19805: Polycomb-Associated Non-Coding RNAs.
MA447879 - JP 2018138019-A/19805: Polycomb-Associated Non-Coding RNAs.
LF378118 - JP 2014500723-A/185621: Polycomb-Associated Non-Coding RNAs.
MA613695 - JP 2018138019-A/185621: Polycomb-Associated Non-Coding RNAs.
LF213168 - JP 2014500723-A/20671: Polycomb-Associated Non-Coding RNAs.
MA448745 - JP 2018138019-A/20671: Polycomb-Associated Non-Coding RNAs.
AY424287 - Homo sapiens progestin and adipoQ receptor family member IX (PAQR9) mRNA, complete cds.
BC118666 - Homo sapiens progestin and adipoQ receptor family member IX, mRNA (cDNA clone MGC:141692 IMAGE:40016554), complete cds.
BC122527 - Homo sapiens progestin and adipoQ receptor family member IX, mRNA (cDNA clone MGC:141693 IMAGE:40016555), complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000340634.1, ENST00000340634.2, ENST00000340634.3, ENST00000340634.4, ENST00000340634.5, NM_198504, PAQR9_HUMAN, Q147T6, Q6ZVX9, uc003evg.1, uc003evg.2, uc003evg.3, uc003evg.4, uc003evg.5, uc003evg.6, uc003evg.7
UCSC ID: ENST00000340634.6
RefSeq Accession: NM_198504
Protein: Q6ZVX9 (aka PAQR9_HUMAN or PAQ9_HUMAN)
CCDS: CCDS3128.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.