Human Gene S100Z (ENST00000317593.9) from GENCODE V44
Description: Homo sapiens S100 calcium binding protein Z (S100Z), mRNA. (from RefSeq NM_130772) RefSeq Summary (NM_130772): Members of the S100 protein family contain 2 calcium-binding EF-hands and exhibit cell-type specific expression patterns. For additional background information on S100 proteins, see MIM 114085.[supplied by OMIM, Mar 2008]. Gencode Transcript: ENST00000317593.9 Gencode Gene: ENSG00000171643.14 Transcript (Including UTRs) Position: hg38 chr5:76,850,014-76,921,650 Size: 71,637 Total Exon Count: 5 Strand: + Coding Region Position: hg38 chr5:76,875,360-76,877,832 Size: 2,473 Coding Exon Count: 2
ID:S100Z_HUMAN DESCRIPTION: RecName: Full=Protein S100-Z; AltName: Full=S100 calcium-binding protein Z; SUBUNIT: Homodimer. Interacts with S100P. TISSUE SPECIFICITY: Highest level of expression in spleen and leukocytes. MISCELLANEOUS: This protein binds two calcium ions. SIMILARITY: Belongs to the S-100 family. SIMILARITY: Contains 2 EF-hand domains.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF01023 - S-100/ICaBP type calcium binding domain
ModBase Predicted Comparative 3D Structure on Q8WXG8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.