Human Gene SSBP2 (ENST00000615665.5) from GENCODE V44
Description: single stranded DNA binding protein 2 (from HGNC SSBP2)
RefSeq Summary (NM_001256732): This gene encodes a subunit of a protein complex that interacts with single-stranded DNA and is involved in the DNA damage response and maintenance of genome stability. The encoded protein may also play a role in telomere repair. A variant of this gene may be associated with survival in human glioblastoma patients. [provided by RefSeq, Sep 2016].
Gencode Transcript: ENST00000615665.5
Gencode Gene: ENSG00000145687.17
Transcript (Including UTRs)
Position: hg38 chr5:81,412,804-81,751,097 Size: 338,294 Total Exon Count: 17 Strand: -
Coding Region
Position: hg38 chr5:81,420,504-81,751,042 Size: 330,539 Coding Exon Count: 17
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
D013749
Tetrachlorodibenzodioxin
C111118
2',3,3',4',5-pentachloro-4-hydroxybiphenyl
C029497
2,3-bis(3'-hydroxybenzyl)butyrolactone
C548651
2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester
C009505
4,4'-diaminodiphenylmethane
D015123
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
D015127
9,10-Dimethyl-1,2-benzanthracene
C547126
AZM551248
D016604
Aflatoxin B1
D000393
Air Pollutants
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AF077048 - Homo sapiens single strand DNA-binding protein mRNA, complete cds.AK294864 - Homo sapiens cDNA FLJ52865 complete cds, highly similar to Single-stranded DNA-binding protein 2.AF161465 - Homo sapiens HSPC116 mRNA, complete cds.CR936787 - Homo sapiens mRNA; cDNA DKFZp686F03273 (from clone DKFZp686F03273).AK074537 - Homo sapiens cDNA FLJ90056 fis, clone HEMBA1003072, weakly similar to Gallus gallus single-strand DNA-binding protein csdp mRNA.AL080076 - Homo sapiens mRNA; cDNA DKFZp564C0362 (from clone DKFZp564C0362).AK297494 - Homo sapiens cDNA FLJ52868 complete cds, highly similar to Single-stranded DNA-binding protein 2.BC017020 - Homo sapiens single-stranded DNA binding protein 2, mRNA (cDNA clone MGC:8958 IMAGE:3913337), complete cds.AK293544 - Homo sapiens cDNA FLJ52881 complete cds, highly similar to Single-stranded DNA-binding protein 2.AK299858 - Homo sapiens cDNA FLJ50198 complete cds, highly similar to Single-stranded DNA-binding protein 2.AK312337 - Homo sapiens cDNA, FLJ92656, highly similar to Homo sapiens single-stranded DNA binding protein 2 (SSBP2), mRNA.KJ893421 - Synthetic construct Homo sapiens clone ccsbBroadEn_02815 SSBP2 gene, encodes complete protein.DQ891620 - Synthetic construct clone IMAGE:100004250; FLH178702.01X; RZPDo839G02128D single-stranded DNA binding protein 2 (SSBP2) gene, encodes complete protein.DQ894812 - Synthetic construct Homo sapiens clone IMAGE:100009272; FLH178698.01L; RZPDo839G02127D single-stranded DNA binding protein 2 (SSBP2) gene, encodes complete protein.EU176592 - Synthetic construct Homo sapiens clone IMAGE:100011583; FLH263627.01L; RZPDo839A03254D single-stranded DNA binding protein 2 (SSBP2) gene, encodes complete protein.EU831646 - Synthetic construct Homo sapiens clone HAIB:100066675; DKFZo007F0919 single-stranded DNA binding protein 2 protein (SSBP2) gene, encodes complete protein.AB528651 - Synthetic construct DNA, clone: pF1KB6541, Homo sapiens SSBP2 gene for single-stranded DNA binding protein 2, without stop codon, in Flexi system.EU831730 - Synthetic construct Homo sapiens clone HAIB:100066759; DKFZo003F0920 single-stranded DNA binding protein 2 protein (SSBP2) gene, encodes complete protein.CU677799 - Synthetic construct Homo sapiens gateway clone IMAGE:100017106 5' read SSBP2 mRNA.JD242943 - Sequence 223967 from Patent EP1572962.JD347339 - Sequence 328363 from Patent EP1572962.JD511527 - Sequence 492551 from Patent EP1572962.JD286689 - Sequence 267713 from Patent EP1572962.JD511528 - Sequence 492552 from Patent EP1572962.JD286690 - Sequence 267714 from Patent EP1572962.JD071032 - Sequence 52056 from Patent EP1572962.JD319485 - Sequence 300509 from Patent EP1572962.JD319484 - Sequence 300508 from Patent EP1572962.JD340699 - Sequence 321723 from Patent EP1572962.JD354776 - Sequence 335800 from Patent EP1572962.JD509940 - Sequence 490964 from Patent EP1572962.JD566283 - Sequence 547307 from Patent EP1572962.JD052588 - Sequence 33612 from Patent EP1572962.JD491282 - Sequence 472306 from Patent EP1572962.JD509324 - Sequence 490348 from Patent EP1572962.JD392371 - Sequence 373395 from Patent EP1572962.JD255310 - Sequence 236334 from Patent EP1572962.JD323725 - Sequence 304749 from Patent EP1572962.JD263266 - Sequence 244290 from Patent EP1572962.JD053708 - Sequence 34732 from Patent EP1572962.JD501162 - Sequence 482186 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A0A087X159, ENST00000615665.1, ENST00000615665.2, ENST00000615665.3, ENST00000615665.4, NR_174560, uc003khp.1, uc003khp.2, uc003khp.3, uc003khp.4, uc003khp.5UCSC ID: ENST00000615665.5RefSeq Accession: NM_001256732
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.