ID:S12A9_HUMAN DESCRIPTION: RecName: Full=Solute carrier family 12 member 9; AltName: Full=Cation-chloride cotransporter 6; Short=hCCC6; AltName: Full=Cation-chloride cotransporter-interacting protein 1; Short=CCC-interacting protein 1; Short=hCIP1; AltName: Full=Potassium-chloride transporter 9; AltName: Full=WO3.3; FUNCTION: May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function. SUBUNIT: Interacts with SLC12A1. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in placenta, brain and kidney. Lower expression in lung, liver and heart. SIMILARITY: Belongs to the SLC12A transporter family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9BXP2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006811 ion transport GO:0055085 transmembrane transport GO:0071805 potassium ion transmembrane transport GO:1902476 chloride transmembrane transport