Human Gene HSD17B3 (ENST00000375263.8) from GENCODE V44
Description: Homo sapiens hydroxysteroid 17-beta dehydrogenase 3 (HSD17B3), mRNA. (from RefSeq NM_000197) RefSeq Summary (NM_000197): This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000375263.8 Gencode Gene: ENSG00000130948.10 Transcript (Including UTRs) Position: hg38 chr9:96,235,306-96,302,176 Size: 66,871 Total Exon Count: 11 Strand: - Coding Region Position: hg38 chr9:96,235,460-96,302,104 Size: 66,645 Coding Exon Count: 11
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6FH62
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
