Human Gene LHFPL1 (ENST00000371968.8) from GENCODE V44
Description: Homo sapiens LHFPL tetraspan subfamily member 1 (LHFPL1), mRNA. (from RefSeq NM_178175) RefSeq Summary (NM_178175): This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000371968.8 Gencode Gene: ENSG00000182508.14 Transcript (Including UTRs) Position: hg38 chrX:112,630,648-112,679,938 Size: 49,291 Total Exon Count: 4 Strand: - Coding Region Position: hg38 chrX:112,631,420-112,671,390 Size: 39,971 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF10242 - Lipoma HMGIC fusion partner-like protein
ModBase Predicted Comparative 3D Structure on Q86WI0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.