Human Gene MIR376A2 (ENST00000636782.1) from GENCODE V44
  Description: Homo sapiens microRNA 376a-2 (MIR376A2), microRNA. (from RefSeq NR_030266)
RefSeq Summary (NR_030266): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage.
Gencode Transcript: ENST00000636782.1
Gencode Gene: ENSG00000283561.1
Transcript (Including UTRs)
   Position: hg38 chr14:101,040,069-101,040,148 Size: 80 Total Exon Count: 1 Strand: +


Page IndexSequence and LinksPrimersOther SpeciesmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:101,040,069-101,040,148)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGencodeHGNCLynxOMIM
PubMedBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  LF209655 - JP 2014500723-A/17158: Polycomb-Associated Non-Coding RNAs.
MA445232 - JP 2018138019-A/17158: Polycomb-Associated Non-Coding RNAs.
DM175431 - A nucleics Acid regulating cell growth.
FV525931 - Nucleic acid controling mast cell degranulation.
HV491981 - WO 2011087154-A/154: Method For Screening Induced Pluripotent Stem Cells.
HW262185 - JP 2013516982-A/154: Method For Screening Induced Pluripotent Stem Cells.
HW505231 - JP 2014502606-A/133: MELANOMA TREATMENTS.
HW505244 - JP 2014502606-A/146: MELANOMA TREATMENTS.
HZ408418 - JP 2015528002-A/1015: CHIRAL CONTROL.
JC208092 - Sequence 154 from Patent EP2524033.
LG051752 - KR 1020150036642-A/1018: CHIRAL CONTROL.
AY785912 - Homo sapiens microRNA hsa-RG-2, complete sequence.
CS548435 - Sequence 1465 from Patent EP1777301.
DJ442731 - Pancreatic Islet microRNA and Methods for Inhibiting Same.
DM174484 - A nucleics Acid regulating cell growth.
FV524374 - Nucleic acid controling mast cell degranulation.
FW312178 - DETECTING NUCLEIC ACIDS.
FW364272 - Oligonucleotides for modulating target RNA activity.
HI561055 - Sequence 270 from Patent EP2190992.
HI561056 - Sequence 271 from Patent EP2190992.
HI965124 - Sequence 409 from Patent WO2010139812.
HI966189 - Sequence 509 from Patent WO2010139811.
HI967055 - Sequence 509 from Patent WO2010139810.
HV036097 - WO 2011027893-A/28: A method for predicting the efficacy of chronic hepatitis C treatment.
HV492042 - WO 2011087154-A/215: Method For Screening Induced Pluripotent Stem Cells.
HV492046 - WO 2011087154-A/219: Method For Screening Induced Pluripotent Stem Cells.
HV594156 - JP 2010538653-A/270: MIRNA EXPRESSION IN HUMAN PERIPHERAL BLOOD MICROVESICLES AND USES THEREOF.
HV594157 - JP 2010538653-A/271: MIRNA EXPRESSION IN HUMAN PERIPHERAL BLOOD MICROVESICLES AND USES THEREOF.
HV595181 - JP 2010539959-A/562: Micromirs.
HV938906 - JP 2011519579-A/1734: Oligonucleotides Containing Arabinose Modified Nucleotides For Treating Inflammation and Neoplastic Cell Proliferation.
HW262246 - JP 2013516982-A/215: Method For Screening Induced Pluripotent Stem Cells.
HW262250 - JP 2013516982-A/219: Method For Screening Induced Pluripotent Stem Cells.
HW505419 - JP 2014502606-A/321: MELANOMA TREATMENTS.
HW505420 - JP 2014502606-A/322: MELANOMA TREATMENTS.
HW505432 - JP 2014502606-A/334: MELANOMA TREATMENTS.
HW505433 - JP 2014502606-A/335: MELANOMA TREATMENTS.
HW669812 - JP 2013537538-A/543: THERAPEUTIC USES OF MICROVESICLES AND RELATED MICRORNAS.
HZ074207 - JP 2013535982-A/298: Single-Stranded RNAi Agents Containing an Internal, Non-Nucleic Acid Spacer.
HZ082880 - JP 2015513906-A/237: Stem Cell Microparticles.
HZ157738 - JP 2015130862-A/562: Micromirs.
HZ186585 - JP 2015146814-A/334: Oligonucleotides for modulating target RNA activity.
HZ436661 - JP 2015529450-A/237: Stem Cell Microparticles.
HZ480372 - JP 2015535430-A/878: TERMINALLY MODIFIED RNA.
HZ790303 - JP 2016504050-A/2048: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JA401162 - Sequence 409 from Patent WO2011080318.
JA402140 - Sequence 409 from Patent WO2011080315.
JA403147 - Sequence 409 from Patent WO2011080316.
JA405778 - Sequence 409 from Patent EP2336353.
JA427161 - Sequence 494 from Patent WO2011072177.
JA429304 - Sequence 409 from Patent WO2011095623.
JA792020 - Sequence 69 from Patent WO2012089753.
JA792313 - Sequence 28 from Patent WO2012089630.
JA821213 - Sequence 1734 from Patent EP2285961.
JB024408 - Sequence 28 from Patent EP2505663.
JB049929 - Sequence 16 from Patent WO2013020926.
JB074784 - Sequence 44 from Patent WO2012168448.
JB136718 - Sequence 28 from Patent EP2476758.
JB175314 - Sequence 346 from Patent WO2012101219.
JB620383 - Sequence 363 from Patent WO2013063544.
JB624450 - Sequence 270 from Patent EP2610342.
JB624451 - Sequence 271 from Patent EP2610342.
JB733811 - Sequence 3214 from Patent WO2013082448.
JB835805 - Sequence 95 from Patent WO2013057567.
JB982237 - Sequence 15 from Patent WO2013190091.
JC037791 - Sequence 319 from Patent EP2643479.
JC171865 - Sequence 237 from Patent WO2013150303.
JC208153 - Sequence 215 from Patent EP2524033.
JC208157 - Sequence 219 from Patent EP2524033.
JC244654 - Sequence 274 from Patent WO2012020308.
JC244899 - Sequence 527 from Patent WO2012020308.
JC270152 - Sequence 543 from Patent WO2012020307.
JC334261 - Sequence 179 from Patent EP2487240.
JC513035 - Sequence 3288 from Patent WO2014113089.
JC572676 - Sequence 237 from Patent WO2014125276.
JC582364 - Sequence 237 from Patent WO2014125277.
JE867507 - Sequence 314 from Patent WO2015128671.
JE954060 - Sequence 237 from Patent WO2015052526.
JE955813 - Sequence 237 from Patent WO2015052527.
LF137565 - JP 2016507550-A/237: Method of Producing Microparticles.
LF160327 - JP 2016513950-A/393: Oligomers with improved off-target profile.
LF162530 - JP 2016513095-A/237: Stem Cell Microparticles and miRNA.
LF953282 - JP 2016534103-A/237: Stem Cell Microparticles and miRNA.
LG005627 - KR 1020150004822-A/237: STEM CELL MICROPARTICLES.
LG053323 - KR 1020150059168-A/237: STEM CELL MICROPARTICLES.
LG240562 - KR 1020160035087-A/237: STEM CELL MICROPARTICLES AND MIRNA.
LP637006 - Sequence 56 from Patent EP2848702.
LP726815 - Sequence 509 from Patent EP2883966.
LP819085 - Sequence 509 from Patent EP3296406.
LP896698 - Sequence 1562 from Patent EP3253886.
LP939027 - Sequence 509 from Patent EP3184651.
LP951743 - Sequence 249 from Patent WO2017157650.
LQ070623 - Sequence 947 from Patent EP2964234.
LQ278735 - Sequence 274 from Patent WO2016066288.
LQ441037 - Sequence 44 from Patent EP3029157.
LV470647 - JP 2016534036-A/237: Stem Cell Microparticles and miRNA.
LX154666 - JP 2017509333-A/314: Biomarkers for Endometriosis.
LX270609 - JP 2016056210-A/543: THERAPEUTIC USES OF MICROVESICLES AND RELATED MICRORNAS.
LY405246 - KR 1020160117535-A/551: POLY OLIGOMER COMPOUND WITH BIOCLEAVABLE CONJUGATES.
LY536152 - KR 1020170120124-A/6: BIOMARKER PANEL FOR THE DETECTION OF CANCER.
LZ215662 - JP 2017518753-A/13: COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF BONE FRACTURES AND DISORDERS.
LZ233942 - JP 2017184756-A/334: Oligonucleotides for modulating target RNA activity.
MA260485 - JP 2017505623-A/551: POLY OLIGOMER COMPOUND WITH BIOCLEAVABLE CONJUGATES.
MA363525 - JP 2018509934-A/6: BIOMARKER PANEL FOR THE DETECTION OF CANCER.
MA419957 - JP 2018518169-A/8: NON-ALCOHOLIC FATTY LIVER DISEASE BIOMARKERS.
MA420039 - JP 2018518169-A/90: NON-ALCOHOLIC FATTY LIVER DISEASE BIOMARKERS.
MA420064 - JP 2018518169-A/115: NON-ALCOHOLIC FATTY LIVER DISEASE BIOMARKERS.
MA420094 - JP 2018518169-A/145: NON-ALCOHOLIC FATTY LIVER DISEASE BIOMARKERS.
MA420108 - JP 2018518169-A/159: NON-ALCOHOLIC FATTY LIVER DISEASE BIOMARKERS.
MA644124 - JP 2017113010-A/2048: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA730756 - JP 2017125065-A/543: THERAPEUTIC USES OF MICROVESICLES AND RELATED MICRORNAS.
MA732008 - JP 2017140048-A/878: TERMINALLY MODIFIED RNA.
MP075724 - Sequence 63 from Patent WO2019002265.
MS833565 - Sequence 270 from Patent EP3112464.
MS833566 - Sequence 271 from Patent EP3112464.
MS834263 - Sequence 409 from Patent EP3112479.
MA801177 - JP 2018183181-A/2048: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MP129337 - Sequence 237 from Patent EP3470073.
MP162260 - Sequence 237 from Patent WO2019069093.
MP280711 - Sequence 131 from Patent WO2019111197.
MP283624 - Sequence 131 from Patent WO2019111198.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_030266, uc021scz.1, uc021scz.2, uc021scz.3
UCSC ID: ENST00000636782.1
RefSeq Accession: NR_030266

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.