Human Gene LINC-ROR (ENST00000553704.3) from GENCODE V44
Description: Homo sapiens long intergenic non-protein coding RNA, regulator of reprogramming (LINC-ROR), transcript variant 1, long non-coding RNA. (from RefSeq NR_048536) RefSeq Summary (NR_048536): This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017]. Gencode Transcript: ENST00000553704.3 Gencode Gene: ENSG00000258609.3 Transcript (Including UTRs) Position: hg38 chr18:57,054,558-57,072,119 Size: 17,562 Total Exon Count: 4 Strand: -
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.