Human Gene CXCR6 (ENST00000438735.1) from GENCODE V44
Description: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. (from UniProt O00574) Gencode Transcript: ENST00000438735.1 Gencode Gene: ENSG00000172215.6 Transcript (Including UTRs) Position: hg38 chr3:45,940,933-45,948,337 Size: 7,405 Total Exon Count: 2 Strand: + Coding Region Position: hg38 chr3:45,946,482-45,947,510 Size: 1,029 Coding Exon Count: 1
ID:CXCR6_HUMAN DESCRIPTION: RecName: Full=C-X-C chemokine receptor type 6; Short=CXC-R6; Short=CXCR-6; AltName: Full=CDw186; AltName: Full=G-protein coupled receptor STRL33; AltName: Full=G-protein coupled receptor bonzo; AltName: CD_antigen=CD186; FUNCTION: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in lymphoid tissues and activated T cells. SIMILARITY: Belongs to the G-protein coupled receptor 1 family. WEB RESOURCE: Name=Wikipedia; Note=CXC chemokine receptors entry; URL="http://en.wikipedia.org/wiki/CXC_chemokine_receptors";
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O00574
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
