Human Gene MT-ND6 (ENST00000361681.2) from GENCODE V44
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Sequence and Links to Tools and Databases
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Primer design for this transcript
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MalaCards Disease Associations
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MalaCards Gene Search: MT-ND6
Diseases sorted by gene-association score: leber optic atrophy* (1180), mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes* (754), leber hereditary optic neuropathy with dystonia* (741), oxyphilic adenoma* (403), leigh syndrome* (187), mitochondrial dna-associated leigh syndrome and narp* (141), melas, mt-nd6-related* (100), mitochondrial complex i deficiency* (86), encephalomyopathy (21), mitochondrial disorders* (19), mitochondrial encephalomyopathy (18), parkinson disease 6, early onset (14), kearns-sayre syndrome (12), optic nerve disease (9), lactic acidosis (7), cranial nerve disease (7), neuropathy (7), cortical blindness (7), dystonia (7), mitochondrial metabolism disease (4), optic atrophy plus syndrome (4), peripheral nervous system disease (1) * = Manually curated disease association
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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Microarray Expression Data
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Orthologous Genes in Other Species
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Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
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Biochemical and Signaling Pathways
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BioCyc Knowledge Library PWY-3781 - aerobic respiration I (cytochrome c)
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Other Names for This Gene
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Alternate Gene Symbols: ENST00000361681.1, U5Z977, uc064xpm.1 UCSC ID: ENST00000361681.2
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GeneReviews for This Gene
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GeneReviews article(s) related to gene MT-ND6: lhon (Leber Hereditary Optic Neuropathy) melas (MELAS) mt-overview (Primary Mitochondrial Disorders Overview) narp (Mitochondrial DNA-Associated Leigh Syndrome and NARP)
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Methods, Credits, and Use Restrictions
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Click here
for details on how this gene model was made and data restrictions if any.
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