Human Gene AVPR1A (ENST00000299178.4) from GENCODE V39
Description: Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA. (from RefSeq NM_000706) RefSeq Summary (NM_000706): The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000299178.4 Gencode Gene: ENSG00000166148.4 Transcript (Including UTRs) Position: hg38 chr12:63,142,759-63,151,201 Size: 8,443 Total Exon Count: 2 Strand: - Coding Region Position: hg38 chr12:63,147,359-63,150,836 Size: 3,478 Coding Exon Count: 2
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.