Human Gene CGA (ENST00000627148.3) from GENCODE V44
Description: Homo sapiens glycoprotein hormones, alpha polypeptide (CGA), transcript variant 2, mRNA. (from RefSeq NM_000735) RefSeq Summary (NM_000735): The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Gencode Transcript: ENST00000627148.3 Gencode Gene: ENSG00000135346.9 Transcript (Including UTRs) Position: hg38 chr6:87,085,498-87,095,106 Size: 9,609 Total Exon Count: 4 Strand: - Coding Region Position: hg38 chr6:87,085,756-87,088,200 Size: 2,445 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6I9S8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.