Human Gene CGB3 (ENST00000357383.4) from GENCODE V44
Description: Homo sapiens chorionic gonadotropin subunit beta 3 (CGB3), mRNA. (from RefSeq NM_000737) RefSeq Summary (NM_000737): This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000357383.4 Gencode Gene: ENSG00000104827.12 Transcript (Including UTRs) Position: hg38 chr19:49,022,869-49,024,333 Size: 1,465 Total Exon Count: 3 Strand: - Coding Region Position: hg38 chr19:49,022,886-49,023,971 Size: 1,086 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.