Gene interactions and pathways from curated databases and text-mining
LEP: top 25 interacting genes (chr7:127881330-127897682)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only LEP-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-LEP interactions     Show top Genes on graph    

Less-frequently mentioned interactions with LEP, not among the Top 25
Other genes interacting with LEP. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

A2M AANAT ABCC6 ACAD8 ADCY1 ADCY10 ADCY2
ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9
ADCYAP1 ADIPOQ ADM AGRP AGTR1 AHSA1 ANG
ANGPT2 APOA4 APOB APOE APOM ATP5O BAAT
BAX BCL10 BCL2 BCL3 BCL5 BCL6 BCL9
CA1 CA2 CA3 CASP1 CASP10 CASP12 CASP14
CASP16 CASP2 CASP3 CASP4 CASP5 CASP6 CASP7
CASP8 CASP9 CAV1 CAV2 CAV3 CCK CCL2
CCL3 CCL4 CCNC CCND1 CCNG1 CD14 CD33
CD36 CD4 CD40 CD46 CD6 CD69 CDK8
CEBPA CEBPB CISH CLU CNR1 CNTF COA1
COA3 COA4 COA5 COA6 CPOX CPT2 CRH
CRHR2 CRK CRP CSN2 CSN3 CSRP1 CTGF
CXCL1 CXCL10 CYP19A1 DIO1 DIO2 DIO3 EDN1
EGF EGFR EGR1 EIF4EBP1 EPO ESR1 ESR2
FAAH FAS FASN FGF2 FGF23 FGFR3 FOS
FUT1 GAL GALP GAST GCG GHRH GHRL
GHSR GNRH2 GRAP2 GSK3B GYS1 GYS2 HIF1A
HK3 HNRNPF HNRNPH1 HSD11B1 HSD11B2 IAPP ICAM1
IFI44 IFNG IGF1 IGF2 IGFBP1 IL10 IL11
IL12A IL12B IL13 IL15 IL16 IL18 IL19
IL1A IL1B IL1RN IL2 IL20 IL21 IL22
IL24 IL25 IL26 IL27 IL2RA IL3 IL31
IL32 IL33 IL34 IL37 IL4 IL5 IL7
IL8 IL9 ING1 ING2 ING3 ING4 ING5
INSR IRAK4 IRF6 IRS1 IRS2 JAK1 JAK3
JUN KDR KISS1 KLK3 LEPROT LIF LIFR
LIPE LPL MAP2K1 MAPK8 MAPK9 MAT2A MC4R
MED1 MED10 MED12 MED13 MED14 MED15 MED16
MED17 MED20 MED21 MED23 MED24 MED25 MED26
MED27 MED31 MED4 MED6 MED7 MED8 MMP1
MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP16
MMP17 MMP19 MMP2 MMP20 MMP21 MMP24 MMP25
MMP26 MMP27 MMP28 MMP3 MMP7 MMP8 MMP9
MSH2 MSH3 MSH4 MSH5 MSH6 MT3 MTOR
MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19
MUC2 MUC20 MUC21 MUC22 MUC4 MUC5B MUC6
MUC7 MUC8 NA NAMPT NFKB1 NFKBIA NGF
NM NMU NOS1 NOS2 NOS3 NOTCH1 NOX1
NOX3 NOX4 NOX5 NPB NPPA NPS NPW
NTS NUP43 PCK1 PCK2 PCNA PCSK1 PDE3B
PGC PI3 PIK3CA PIK3R1 PLA2G4A POLDIP2 POMC
PPARA PPARG PPY PRKAA1 PRKAA2 PRKAB1 PRKAB2
PRKACB PRKACG PRKAG1 PRKAG2 PRKAG3 PRKAR1A PRKAR1B
PRKAR2A PRKAR2B PRL PTBP1 PTBP2 PTEN PTGS2
PTH PTPN1 PTPN11 RAC1 REG1A RELA RENBP
RETN RHOA RNF19A ROCK1 ROCK2 RUNX2 SCD
SETD2 SH2B1 SH2B2 SH2B3 SHBG SIGLEC6 SLC10A2
SLC2A2 SLC2A4 SLC5A1 SLPI SOAT1 SOCS1 SOCS3
SOD1 SOD2 SOD3 SP1 SRC SREBF1 SST
STAR STAT1 STAT5A STAT5B SYT1 TAPBP TCF12
TCF15 TCF19 TCF20 TCF21 TCF23 TCF24 TCF25
TCF3 TCF4 TCF7 TFPI TGFB1 TGFB2 TGFB3
TGFBR2 TH THRAP3 TIMP1 TLR1 TLR10 TLR2
TLR3 TLR4 TLR5 TLR6 TLR7 TLR8 TLR9
TNFRSF11B TPM1 TPM2 TPM3 TPM4 TRH TSHB
TYR UCN UCP1 UCP2 UCP3 VEGFA
Data information
Please see the Gene Interactions Track Manual.