We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining
SIRT1: top 25 interacting genes (chr10:69644426-69678147)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SIRT1-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-SIRT1 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with SIRT1, not among the Top 25
Other genes interacting with SIRT1. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AASDHPPT ACACA ACSS2 ADAM10 AEBP2 AFF4 AGO1
AHCY AHCYL1 AHCYL2 AKIP1 AKIRIN2 AR ARHGAP29
ARID4B ARNT ARNTL ARRB2 ATG5 ATG7 ATP1A1
ATXN7L2 ATXN7L3 ATXN7L3B BAHD1 BAX BAZ2A BCL10
BCL11A BCL11B BCL2 BCL2L11 BCL3 BCL5 BCL6
BCL9 BHLHE41 BRD4 CACNA1C CAP1 CCAR2 CCDC101
CCNB1 CCNT1 CDK1 CDK6 CDK9 CDKL1 CDKN1A
CDKN1B CEBPA CHCHD2 CHD3 CIITA CLOCK CMYA5
CNOT1 CNOT10 CREB1 CREB3 CREB5 CREBBP CREBZF
CRTC2 CSNK1E CSNK2A1 CSNK2A1P CSNK2A2 CSNK2B DBP
DCAF16 DDOST DEDD DGKA DIAPH3 DICER1 DNAJA2
DNAJB1 DNMT3B DOT1L DYNC1H1 DYRK1A E2F1 ECT2
EDIL3 EED EEF1A1 EEF1G EGR1 EIF2B4 ELAVL1
ELL3 ENY2 EPHB2 EPO ESRRA FAM98A FASN
FBN2 FBXO3 FGF21 FKBP1A FOS FOXO3 FOXO4
FOXO6 FXR1 FXR2 G6PC GABARAPL1 GTF2A1 H2AFX
H2AFY2 H2AFZ H3F3A HCFC1 HCFC2 HDAC1 HDAC2
HEY2 HIC1 HIST1H1B HIST1H1E HIST1H2BD HIST1H3A HIST1H4A
HIST1H4C HIST2H2AB HIST2H3A HIST3H3 HNF1A HNF4A HNRNPH3
HNRNPK HNRNPUL1 HSP90AA1 HSP90AB1 HSPA1A HSPA1L HSPA4
HSPA5 HSPA8 HSPA9 HSPD1 IGF1 ING1 ING2
IPO9 IQCB1 IRF6 IRS1 IRS2 ITPK1 JAK1
JARID2 JUN JUND KAT2A KAT2B KAT5 KIAA1598
KIF7 KLHL23 KPNA2 KPNA3 KRT79 KYNU LAMA3
LANCL1 LTA4H MAP1A MAP1B MAP1LC3B MAP1S MAP2K4
MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15
MAPK3 MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MAPT
MCF2L2 MCM10 MCM3 MECOM MEF2C MEF2D MIR34A
MLLT1 MLLT3 MMP9 MRE11A MTF2 MTOR MYC
MYOD1 NAMPT NANOG NAT10 NBN NCOR1 NCOR2
NEDD4 NEDD8 NEUROD1 NEUROD2 NEUROD4 NEUROD6 NFE2L2
NFKB1 NHLH2 NMNAT1 NOC4L NOP14 NOS2 NOTCH1
NOTCH2 NOTCH3 NOTCH4 NOX1 NOX3 NOX4 NOX5
NPM1 NR0B2 NR1H2 NR1H3 NR1H4 NR5A2 NRF1
NUDCD2 NUDT21 ORC1L PAPOLA PARP1 PARP10 PARP11
PARP12 PARP14 PARP15 PARP16 PARP2 PARP3 PARP4
PARP6 PARP8 PARP9 PCNA PDCD1 PHF1 PHF19
PHLDB3 PIAS2 PIAS3 PICALM PIK3CA PIK3R1 PIP5K1A
POFUT2 PPARA PPARG PPARGC1A PPM1G PREPL PRMT5
PSMA2 PSMA4 PSMA7 PSMB5 PTPN1 PUS7 RAD50
RAP1A RARA RB1 RBBP4 RBBP7 RBM25 RBP1
RECQL4 RETN ROCK1 RPL23 RPL38 RPS27L RPS3
RRP8 RUVBL2 SART1 SART3 SCNM1 SERPINB4 SET
SKI SLC22A3 SLC25A13 SLC25A3 SLC25A5 SLC25A6 SMAD7
SMARCA5 SMARCD2 SND1 SNW1 SOD1 SOD2 SOD3
SOST SPDL1 SREBF1 SRRM2 SSR1 STAT3 STK11
STK4 SUPT20H SUPT3H SUPT7L SUZ12 SYNCRIP TADA1
TADA2B TADA3 TAF1A TAF1B TAF1C TAF1D TAF2
TAF5L TAF6L TAF9 TARBP2 TAT TBP TFAM
TFDP1 TFDP2 TLE1 TMEM33 TP73 TPM4 TRIM28
TRRAP TSC2 TSPYL1 TULP3 UBC UBE2O UCP2
UGDH USP11 USP22 USP27X USP9Y UVSSA VDR
WDR70 WDR77 WNK1 WRN XPA YBX1 ZBTB7A
ZEB1 ZFP91 ZNF346 ZNF579 ZNHIT6

Data information
Please see the Gene Interactions Track Manual.