Gene interactions and pathways from curated databases and text-mining

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BMP1 — BMP2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: BMP1 — BMP2 (interaction, mapped from grid)
  • STRING interaction: BMP2 — BMP1 (interaction, mapped from kegg_pathways)

Text-mined interactions from Literome

Pappano et al., Mol Cell Biol 2003 : However, in vivo evidence of roles for BMP-1 and mTLL-1 in BMP signaling in mammals is lacking
Kim et al., J Biol Chem 2004 : Its expression is stimulated by bone morphogenetic protein (BMP)-2 treatment, the activation of BMP receptors and R-Smads, and the expression of Dlx5 and Runx2
Li et al., J Spinal Disord Tech 2004 : Effect of bone morphogenetic protein-2 (BMP-2) on matrix production, other BMPs, and BMP receptors in rat intervertebral disc cells ... An in vitro experiment study using rat disc cells was carried out to determine the effect of bone morphogenetic protein-2 (BMP-2) on extracellular matrix production, other BMPs, and BMP receptors ( BMPRs )
Nobta et al., J Biol Chem 2005 : Furthermore, our data also suggest that functional Notch signaling is essential not only for BMP2 induced osteoblast differentiation but also for BMP signaling itself
Ryoo et al., Gene 2006 : The establishment of an in vitro model system has enabled the investigation of intracellular events including BMP receptor activation, BMP-2 induced R-Smad activation , and kinase activation, and the role of osteogenic transcription factors, such as Runx2, Osx, Dlx5, and Msx2
Zachos et al., J Orthop Res 2006 : Adenovirus ( Ad ) -BMP-2 and Ad-BMP-6 transduction resulted in abundant BMP-2 and BMP-6 mRNA and protein expression in monolayer culture and BMP-2 protein expression in alginate cultures
Schlueter et al., Dev Biol 2006 : In order to assess its functional role, BMP signaling was experimentally modulated by supplying exogenous BMP2 and by inhibiting endogenous BMP signaling through the addition of Noggin
Rifas et al., J Cell Biochem 2007 : Reverse transcriptase-polymerase chain reaction ( RT-PCR ) analysis showed that T-cell cytokines induced noggin, Runx2, BMP-2 , and osteocalcin gene expression, while noggin alone induced BMP-2 and osteocalcin gene expression, but not Runx2, although it increased the expression of ActRII, a receptor for BMP-2
Xia et al., J Biol Chem 2007 : Furthermore, in BmpRII-null pulmonary artery smooth muscle cells, BMP2 and BMP4 signaling was reduced by inhibition of endogenous RGMa expression, and RGMa mediated BMP signaling required ActRIIA expression
Foppiano et al., Dev Biol 2007 : These data indicate that BMP signaling mediates interactions between tissues in the FNP that regulate FEZ formation ; and that the correct pattern of Bmp2 and Bmp4, but not Bmp7, expression in the FNP mesenchyme requires signaling by the BMP pathway
Schwartz et al., J Orthop Res 2008 : BMP-2 was stimulatory over OM, and PEMF + BMP-2 synergistically increased ALP and osteocalcin
Miyoshi et al., J Med Invest 2008 : After confirming that BMP2 could activate the canonical BMP-Smads signaling in HAT-7 cells, we analyzed the effects of BMP2 on 14,815 gene expressions and profiled them
Canty-Laird et al., Biol Reprod 2010 : BMP1 also promotes BMP signaling by releasing BMP signaling molecules from complexes with the BMP-antagonist chordin
Oh et al., J Bone Miner Res 2012 : PlxnA2 was associated with both type 1 and 2 BMP receptors, and BMP2 increased the interaction between PlxnA2 and type 1 receptors
Gerjevic et al., International journal of hepatology 2012 : In summary, alcohol stimulates TGF-beta and BMP2 expression, and Smad2 phosphorylation but inhibits BMP receptor, and Smad1 and Smad5 activation
Kwon et al., Biochem Biophys Res Commun 2012 : It was also found that TGF-ß1 but not BMP2 induced ATP oscillations and inhibition of TGF-ß but not BMP signaling prevented insulin induced ATP oscillations
Tovar-Vidales et al., Invest Ophthalmol Vis Sci 2013 : The purpose of our study was to determine whether cultured human trabecular meshwork ( TM ) cells express BMP1, BMP1 expression is regulated by TGF-ß2, BMP1 is biologically active, and BMP1 regulates LOX activity
Chen et al., Calcif Tissue Int 1997 : These results suggest that BMP-2 enhances expression of other BMP genes during bone cell differentiation