Gene interactions and pathways from curated databases and text-mining

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BMP6 — MAPK14

Text-mined interactions from Literome

Viñals et al., FEBS Lett 2002 : In contrast, BMP-2 had no effect on p42/p44 MAPK ( Erks ) stimulation
Darby et al., J Pathol 2008 (Neoplasm Invasiveness...) : BMP-6 stimulation also led to an increase in phosphorylation levels of MAPK proteins
Takahashi et al., J Endocrinol 2008 : Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen induced proliferation of breast cancer cells by suppressing p38 mitogen activated protein kinase activation ... Estradiol rapidly activated MAPK phosphorylation including extracellular signal regulated kinase 1/2, p38, and stress activated protein kinase/c-Jun NH2-terminal kinase pathways and BMP6 , BMP7, and activin preferentially inhibited estradiol induced p38 phosphorylation
Leong et al., PloS one 2009 (Osteoporosis) : These results indicate that protein palmitoylation plays an important role in BMP induced MAPK activation, osterix expression, and osteoblast differentiation
Ge et al., J Bone Miner Res 2012 (MAP Kinase Signaling System) : Significantly, in the presence of AA, BMP2/7 synergistically stimulated RUNX2 S319 phosphorylation and transcriptional activity without affecting total RUNX2 and this response was totally dependent on ERK/MAPK activity
Ebeling et al., Reprod Fertil Dev 2011 : Furthermore, BMP-6 did not affect the activity of the mitogen activated protein kinase
Yumoto et al., J Biol Chem 2013 (Cleft Palate) : Our studies show that in neural crest derived craniofacial ecto-mesenchymal cells, Tak1 is not only required for TGF-ß- and bone morphogenetic protein induced p38 Mapk activation but also plays a role in agonist induced C-terminal and linker region phosphorylation of the receptor mediated R-Smads