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CALM1 — IL8
Text-mined interactions from Literome
Nozawa et al., Biochem Pharmacol 2002
:
H. pylori induced
IL-8 production is dominantly
regulated by
Ca2+/calmodulin signaling, and ERK plays an important role in signal transmission for the efficient activation of H. pylori induced NF-kappaB activity, resulting in IL-8 production
Ito et al., J Biol Chem 1991
:
These results indicate that
calmodulin is
required for the
interleukin 1-enhanced synthesis of TIMP but it is a suppressor for the synthesis of proMMPs-1 and -3
Shen et al., J Nutr 2013
(Inflammation...) :
U73122 attenuated 18 : 2t10, c12 mediated insulin resistance within 48 h and suppression of the mRNA levels of peroxisome proliferator activated receptor ( PPAR ) ?, insulin stimulated glucose transporter-4, acetyl-CoA carboxylase-1, and stearoyl-CoA desaturase-1, and the protein levels of PPAR? within 18-24 h. U73122 inhibited 18 : 2t10, c12 mediated induction of the inflammatory related genes
calcium/calmodulin dependent protein kinase-ß, cyclooxygenase-2, monocyte chemoattractant protein-1, interleukin (IL)-6, and
IL-8 , secretion of IL-6 and IL-8, and the activation of extracellular signal related kinase, c-Jun N-terminal kinase, and c-Jun within 18-24 h