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CCND1 — CDK3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Chang et al., Int J Oncol 2000
(Neoplasms, Experimental) :
Inhibition of
cyclin D1 expression or
induction of
cyclin dependent kinase inhibitor p21WAF1 expression was found in mimosine treated lung cancer cells
Osborne et al., Br J Dermatol 2002
(Breast Neoplasms...) :
1,25 ( OH ) 2D3 has a major inhibitory effect on the G1/S checkpoint of the cell cycle by upregulating the
cyclin dependent kinase inhibitors p27 and p21, and by
inhibiting cyclin D1
Brennan et al., J Med Food 2012
(Adrenocortical Carcinoma) :
BME treatment enhanced cellular tumor antigen p53,
cyclin dependent kinase inhibitor 1A ( also called p21 ), and cyclic AMP dependent transcription factor-3 levels and
inhibited G1/S-specific cyclin D1 , D2, and D3, and mitogen activated protein kinase 8 ( also called Janus kinase ) expression, suggesting an additional mechanism involving cell cycle regulation and cell survival
Kang et al., Apoptosis 2012
:
Cell cycle analysis indicated thioridazine induced the down-regulation of
cyclin D1 , cyclin A and CDK4, and the induction of p21 and p27, a
cyclin dependent kinase inhibitor