Wang et al., Cancer Res 2002
:
Ku affects the ataxia and Rad 3-related/CHK1 dependent S phase checkpoint response after camptothecin treatment
Ray et al., Mol Cancer Ther 2007
(Prostatic Neoplasms) :
The combination treatment induced an S-phase checkpoint response through activation of Chk2 and Chk1 by the ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3 related kinases, leading to phosphorylation and decreased Cdc25A levels