Gene interactions and pathways from curated databases and text-mining

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ESR2 — PTGS2

Text-mined interactions from Literome

Fauti et al., FEBS J 2006 : Here, we show that the 4-hydroxytamoxifen ( 4-OHT ) mediated activation of a C-Raf-estrogen receptor fusion protein leads to the induction of both the PPARbeta and Cox-2 genes, concomitant with a dramatic increase in PGI2 synthesis
Su et al., Am J Obstet Gynecol 2009 : Estrogen receptor-beta mediates cyclooxygenase-2 expression and vascular prostanoid levels in human placental villous endothelial cells ... ESR2 mediates COX-2 expression levels and both prostacyclin and thromboxane concentrations in the basal state, which suggests the possibility of ligand independent regulation of COX-2 activity and prostaglandin H2 substrate availability