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EGFR — FGF2

Pathways - manually collected, often from reviews:

• KEGG Melanoma: EGF/FGF1/FGF10/FGF11/FGF12/FGF13/FGF14/FGF16/FGF17/FGF18/FGF19/FGF2/FGF20/FGF21/FGF22/FGF23/FGF3/FGF4/FGF5/FGF6/FGF7/FGF8/FGF9/HGF/IGF1/PDGFA/PDGFB/PDGFC/PDGFD → EGFR/FGFR1/IGF1R/MET/PDGFRA/PDGFRB (protein-protein, activation)
  
• WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: EFNA1/FGF1/FGF11/FGF10/EFNA2/EGF/FGF12/CSF1/ANGPT4/ANGPT2/ANGPT1/VEGFA/EFNA3/EFNA4/EFNA5/FGF14/FGF19/FGF17/FGF18/FGF2/FGF3/FGF4/FGF6/FGF7/FGF8/FGF9/FIGF/HGF/IGF1/INS/INS/KITLG/VEGFC/VEGFB/PDGFB/PGF/PDGFA/NGF/PDGFC/FGF21/FGF22/PDGFD/FGF20/FGF16 → FGFR2/KDR/INSR/FGFR3/IGF1R/KIT/FGFR1/EPHA2/EGFR/CSF1R/FGFR4/FLT1/FLT4/NGFR/MET/PDGFRA/PDGFRB/TEK (activation)
  

Text-mined interactions from Literome

Huang et al., J Surg Res 2003 (Adenocarcinoma...) : 1 ) Association of Grb2 to EGFR in BxPC-3 induced by EGF in the presence of Erbitux indicates an alternate pathway of Ras-MAPK activation, which may be related with the tumor resistance to treatment ; 2 ) transactivation of EGFR downstream Ras-MAPK pathway by FGF contributes the resistance to treatment ; and 3 ) downregulation of EGFR may increase the response to therapy
Chen et al., Hua Xi Kou Qiang Yi Xue Za Zhi 2009 : [ Effect of basic fibroblast growth factor on the gene expression of epidermal growth factor receptor by periodontal ligament cells in culture ] ... To study the effect of basic fibroblast growth factor (bFGF) on the gene expression of epidermal growth factor receptor (EGFR) by periodontal ligament cells ( PDLC ) in culture and discuss the effect of bFGF in cell differentiation and periodontal regeneration ... The mRNA expression of EGFR was promoted by bFGF and the effect was dose dependent