Gene interactions and pathways from curated databases and text-mining

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FLT1 — IL3

Text-mined interactions from Literome

Testa et al., Blood 1996 : In quiescent HPCs the receptors for early acting [ flt3 ligand (FL), c-kit ligand (KL), bFGF, interleukin-6 (IL-6) ] and multilineage [ IL-3, granulocyte-macrophage CSF (GM-CSF) ] HGFs are expressed at significant levels but with different patterns, eg, kit and flt3 are detected on a majority and minority of HPCs, respectively, whereas IL-3Rs and GM-CSFRs are present on almost all HPCs
Tisdale et al., Blood 1998 : Stem cell factor (SCF)/granulocyte colony stimulating factor ( G-CSF ) -mobilized and CD34 enriched PB cells were divided into two equal aliquots and transduced with one of two retroviral vectors carrying the neomycin-resistance gene ( neo ) for 4 days in the presence of interleukin-3 (IL-3) , IL-6, and SCF in the first 5 animals, IL-3/IL-6/SCF/Flt-3 ligand (FLT) in 2 subsequent animals, or IL-3/IL-6/SCF/FLT plus an autologous stromal monolayer ( STR ) in the final 2