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FXR2 — SREBF1

Text-mined interactions from Literome

Jiang et al., Diabetes 2007 (Diabetic Nephropathies...) : In renal mesangial cells, overexpression of FXR or treatment with GW4064 also inhibited SREBP-1c and other lipogenic genes, transforming growth factor-beta, and interleukin-6, suggesting a direct role of FXR in modulating renal lipid metabolism and modulation of fibrosis and inflammation
Wang et al., American journal of physiology. Renal physiology 2009 (Fibrosis...) : In the current study, we have determined a key role of the farnesoid X receptor ( FXR ) in modulating renal SREBP-1 activity, glomerular lesions, and proteinuria
Mencarelli et al., PloS one 2010 (Atherosclerosis...) : Natural and synthetic FXR ligands reduced the nuclear translocation of SREBP1c caused by ritonavir