Song et al., Gastroenterology 2007
:
Like insulin, GIP induced the activation of Akt in a concentration dependent manner, promoted membrane glucose transporter-4 accumulation, and enhanced [ ( 3 ) H ] -2-deoxyglucose uptake
Shu et al., Hum Mol Genet 2009
:
Loss of TCF7L2 resulted in decreased GLP-1 and GIP stimulated AKT phosphorylation, and AKT mediated Foxo-1 phosphorylation and nuclear exclusion