Gene interactions and pathways from curated databases and text-mining

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GPR88 — INS

Text-mined interactions from Literome

Dalle et al., Mol Cell Biol 2002 (MAP Kinase Signaling System) : Insulin induces heterologous desensitization of G-protein coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1
Bavirti et al., Metabolism 2003 (Diabetes Mellitus, Type 2...) : The steeper decrease in GPR may have been due to a greater insulin response to oral glyburide in those with IFG
Lan et al., Br J Pharmacol 2012 : However, in Min6 cells, GPR119 mediated insulin secretion was glucose dependent
Schwetz et al., Am J Physiol Endocrinol Metab 2013 (Calcium Signaling) : Pancreatic ß-cells regulate glucose homeostasis by secreting insulin in response to glucose elevation and G protein coupled receptor ( GPCR ) activation
Matsuda-Nagasumi et al., Diabetes Obes Metab 2013 (Diabetes Mellitus, Experimental...) : G protein coupled receptor/free fatty acid receptor 1 ( GPR40/FFAR1 ) regulates free fatty acid induced insulin secretion