Gene interactions and pathways from curated databases and text-mining

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CASP14 — GPX3

Text-mined interactions from Literome

Wang et al., J Biol Chem 2012 (Prostatic Neoplasms) : The induced expression of GPx3 in DU145 and PC3 cells resulted in an increase in reactive oxygen species and caspase-3 activity
Yang et al., Int Immunopharmacol 2013 (Disease Models, Animal...) : XN significantly decreased malondialdehyde, potentiated superoxide dismutase and glutathione peroxidase , reduced Bax expression, promoted Bcl-xL and inhibited caspase 3 activity in liver tissues compared with the animals without XN intervention