Gene interactions and pathways from curated databases and text-mining

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HDAC8 — IRF6

Text-mined interactions from Literome

Aung et al., FASEB J 2006 (Inflammation) : LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression
Zhang et al., J Cardiovasc Pharmacol 2012 (Disease Models, Animal...) : Moreover, blockade of GC-GR signaling pathway by adrenalectomy, RU486 or TSA enhanced LPS induced myocardial nuclear factor-?B activation and histone acetylation but inhibited myocardial histone deacetylase expression and activity