Gene interactions and pathways from curated databases and text-mining

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ATP5O — HSPG2

Text-mined interactions from Literome

Banday et al., American journal of physiology. Renal physiology 2007 (Obesity) : Lean and obese rats were given normal diet or diet supplemented with antioxidant lipoic acid for 2 wk. Compared with lean rats, obese rats exhibited oxidative stress, D1R were uncoupled from G ( q/11 ) alpha at basal level, and SKF-38393 failed to elicit D1R-G protein coupling, stimulate phospholipase C (PLC) , and inhibit Na-K-ATPase activity ... GRK2 interacts with G ( q/11 ) alpha and acts, at least in part, as a regulator of G protein signaling leading to the D1R-G ( q/11 ) alpha uncoupling, causing inability of SKF-38393 to stimulate PLC and inhibit Na/K-ATPase
Lin et al., Endocrinology 2010 (Calcium Signaling) : Furthermore, the specific inhibition of MyH9 ATPase activity with Blebbistatin dose-dependently suppressed FSH induced G alpha h/PLC-delta 1 signaling and Ca ( 2+ ) -influx, but not intracellular cAMP accumulation in rat SCs, implying that MyH9 mediates FSH induced activation of G alpha h/PLC-delta 1/IP ( 3 ) /Ca ( 2+ ) -influx pathway in rat SCs
Suzuki et al., J Mol Cell Cardiol 1993 : In order to understand interactions between oxidants and non-antioxidants, relationships between the effects of superoxide anion radical ( O2- ) and palmitoyl-L-carnitine (PLC) on the Ca ( 2+ ) -ATPase of vascular smooth muscle sarcoplasmic reticulum were studied ... These results demonstrate that O2- can inhibit stimulatory effects of PLC on the Ca ( 2+ ) -ATPase , however, PLC does not block the inhibitory effect of O2-