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BMP2 — IGF1

Text-mined interactions from Literome

Takahashi et al., Int J Mol Med 2007 : Bone morphogenetic protein-2 and -9 regulate the interaction of insulin-like growth factor-I with growth plate chondrocytes ... BMP-2 , but not BMP-9 increased IGF-I binding to growth plate chondrocytes in kinetic studies
Wahdan-Alaswad et al., Cancer Res 2010 (Prostatic Neoplasms) : Insulin-like growth factor I suppresses bone morphogenetic protein signaling in prostate cancer cells by activating mTOR signaling
Wu et al., PloS one 2012 : In conclusion, our study suggests that LPLI may induce IGF1 expression to promote both the proliferation and osteogenic differentiation of D1 cells, whereas it may induce BMP2 expression primarily to enhance osteogenic differentiation
Monjo et al., International journal of biomaterials 2012 : Moreover, OsseoSpeed surface increased BMP-2 secretion after 2 days, and this was followed by increased IGF-I , BSP, and osterix gene expression and mineralization compared to TiOblast after 14 days
Gabbitas et al., Endocrinology 1995 : Previous work from our laboratory indicated that bone morphogenetic protein-2 (BMP-2) enhances the synthesis of insulin-like growth factor-I (IGF-I) and IGF-II by skeletal cells