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IGF1 — RAD51

Text-mined interactions from Literome

Tamburini et al., Blood 2008 (Leukemia, Myeloid, Acute) : This mTOR C1-mediated Akt up-regulation was explained by an insulin-like growth factor-1 (IGF-1)/IGF-1 receptor autocrine loop : ( 1 ) blast cells expressed functional IGF-1 receptors, and IGF-1 induced Akt activation was increased by RAD001 , ( 2 ) a neutralizing anti-IGF-1R alpha-IR3 monoclonal antibody reversed the RAD001 induced Akt phosphorylation, and ( 3 ) autocrine production of IGF-1 was detected in purified blast cells by quantitative reverse transcription-polymerase chain reaction and immunofluorescence
Paek et al., Mol Cells 2011 (Colonic Neoplasms) : Furthermore, the knockdown of GIPC reduced the expression of Rad51 , which is regulated by ZNF143, in response to IGF-1 in colon cancer cells