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IGFBP2 — IL6
Text-mined interactions from Literome
Feliers et al., Br J Haematol 1999
(Multiple Myeloma) :
In contrast,
IGFBP4 was not regulated in
response to
IL-6 , TNF-alpha, PDGF BB, bFGF, TGF-beta or the cAMP agonist, forskolin
Street et al., J Endocrinol 2003
:
On day 4, IL-1beta ( 1 ng/ml ) and
IL-6 ( 10 and 50 ng/ml )
reduced IGFBP-2 by 29+/-8 %, and by 32+/-9 and 38+/-8 % respectively ( P < 0.05 ) ... Both
IGFBP-2 and IGFBP-4 were
reduced by IL-1beta and
IL-6 in combination at 1 and 10 ng/ml ( P < 0.05 ) ... IL-1beta and
IL-6 in combination at 1 and 10 ng/ml
reduced both
IGFBP-2 and IGFBP-4.In conclusion, IGFBP-2 and IGFBP-4 secretion in CM decreased with Caco-2 cell differentiation