We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to MTOR

IL12B — MTOR

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Cheekatla et al., Med Microbiol Immunol 2012 (Leishmaniasis, Visceral) : We show for the first time that in THP-1 derived macrophages and human monocytes, mTOR inhibition by rapamycin reversed L. donovani induced IL-12 and IL-10 modulation
Kusaba et al., J Biol Chem 2005 : IL-12 induced phosphorylation of Stat3 on Ser-727 was affected by rapamycin, which may be due to the effect of rapamycin on the IL-12 induced interaction between mammalian target of rapamycin (mTOR) and Stat3
Ohtani et al., Blood 2008 (Leishmaniasis, Cutaneous) : Rapamycin, an inhibitor of mTOR, enhanced IL-12 production in LPS stimulated DCs, whereas the activation of mTOR by lentivirus mediated transduction of a constitutively active form of Rheb suppressed the production of IL-12