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IL22 — PTGS2

Text-mined interactions from Literome

Fosslien et al., Ann Clin Lab Sci 2000 (Carcinoma, Squamous Cell...) : COX-2 is inducible by oncogenes ras and scr, interleukin-1 , hypoxia, benzo [ a ] pyrene, ultraviolet light, epidermal growth factor, transforming growth factor beta, and tumor necrosis factor alpha
Nédélec et al., Biochem Pharmacol 2001 : In monolayers, interleukin-1beta (IL-1beta) induced COX-2 and NOS II expression in a dose- and time dependent manner, to produce high prostaglandin E ( 2 ) ( PGE ( 2 ) ) and nitrite ( NO ( 2 ) ( - ) ) levels in an apparently coordinated fashion
Moore et al., J Appl Physiol 2001 : In human cultured airway smooth muscle cells, interleukin (IL)-1 beta increases cyclooxygenase (COX)-2 expression and PGE ( 2 ) release, ultimately resulting in decreased beta-adrenergic responsiveness
Soloff et al., Endocrinology 2004 : In situ analysis of interleukin-1 induced transcription of cox-2 and il-8 in cultured human myometrial cells
Stamp et al., J Rheumatol 2004 : Paracrine upregulation of monocyte cyclooxygenase-2 by mediators produced by T lymphocytes : role of interleukin 17 and interferon-gamma
Attar et al., Hum Reprod Update 2006 (Endometriosis...) : COX-2 in turn is stimulated by E ( 2 ), interleukin-1beta (IL-1beta) and PGE ( 2 ) itself in endometrial and endometriotic cells
Wu et al., Prostaglandins Other Lipid Mediat 2007 : In this review, we provide evidence for reduced COX-2 transcriptional expression in response to phorbol esters ( PMA ), lipopolysaccharide (LPS), interleukin-1beta (IL-1beta) and tumor necrosis factor alpha (TNFalpha)
Wu et al., Reprod Sci 2007 (Endometriosis) : These results, along with recent findings that TSA suppresses proliferation, interleukin-1 beta induced cyclo-oxygenase 2 expression, and constitutive or TNFalpha stimulated nuclear factor kappa B activation in endometrial and endometriotic cells, makes histone deacetylase inhibitors a promising class of compounds for novel and more effective medical treatment of endometriosis, especially given the mounting evidence that endometrios be an epigenetic disease
Vinukonda et al., Brain 2010 (Disease Models, Animal...) : Cyclooxygenase-2 or prostanoid receptor-1 inhibition reduced tumour necrosis factor-a level, but not interleukin-1ß
Martín et al., J Hypertens 2012 : PPAR? activation with pioglitazone reduces interleukin-1ß induced COX-2 expression by interference with the redox-sensitive transcription factor NF-?B ... This study analyzes the effect of pioglitazone, a PPAR? agonist, on interleukin-1ß induced COX-2 expression and the role of reactive oxygen species ( ROS ) on this effect
Seo et al., Immunopharmacol Immunotoxicol 2012 (Inflammation) : SPEE treatment significantly inhibited the LPS induced production of NO, prostaglandin E ( 2 ), interleukin-6 , and tumor necrosis factor-a and inhibited the expression of iNOS and COX-2 via attenuation of NF-?B p65 expression
Szczepanski et al., Arthritis Rheum 1994 : Induction of cyclooxygenase II in human synovial microvessel endothelial cells by interleukin-1
Feng et al., Arch Biochem Biophys 1993 : In rat vascular smooth muscle cells, interleukin-1 beta selectively increased the expression of COX-2 , but not that of COX-1, as assessed by enzyme activity, immunoprecipitation of COX proteins, and mRNA analysis
Crofford et al., Arthritis Rheum 1997 (Arthritis, Rheumatoid) : Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes
Kniss et al., Am J Obstet Gynecol 1997 : Interleukin-1 receptor antagonist blocks interleukin-1 induced expression of cyclooxygenase-2 in endometrium ... Experiments were conducted to examine whether interleukin-1 receptor antagonist could suppress interleukin-1 induced cyclooxygenase-2 expression
Staels et al., Nature 1998 (Coronary Disease...) : In these smooth-muscle cells, we find that PPARalpha ligands, and not PPARgamma ligands, inhibit interleukin-1 induced production of interleukin-6 and prostaglandin and expression of cyclooxygenase-2
Longo et al., Mediators Inflamm 1998 : The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation