Gene interactions and pathways from curated databases and text-mining

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ITGA4 — TNF

Text-mined interactions from Literome

Hideshima et al., Oncogene 2001 (MAP Kinase Signaling System...) : TNFalpha in both a dose and time dependent fashion induced expression of CD11a ( LFA-1 ), CD54 ( intercellular adhesion molecule-1, ICAM-1 ), CD106 ( vascular cell adhesion molecule-1, VCAM-1 ), CD49d ( very late activating antigen-4, VLA-4 ), and/or MUC-1 on MM cell lines ; as well as CD106 ( VCAM-1 ) and CD54 ( ICAM-1 ) expression on BMSCs
Lee et al., Chem Biol Interact 2011 (Leukemia, Monocytic, Acute) : Rh1 and CK dampened induction of counter-receptors, a4/ß1 integrin VLA-4 and aL/ß2 integrin LFA-1 in TNF-a treated THP-1 cells